About us

This Nordic Center of Excellence gathers 12 prominent research groups from Denmark, Finland, Norway and Sweden. We collaborate closely and use a variety of different research techniques at the forefront of modern science to try to understand what Alzheimer's disease (AD), Parkinson's disease (PD) and Huntington's disease (HD) have in common and if they can be prevented with new treatments.

Diseases affecting the brain and spinal cord are important causes of both disability and early death. Due to high costs for treatment, care and lost working years, they also represent a major financial burden to society. These diseases include Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and Creutzfeld-Jacob disease. In general, current treatments are unsatisfactory. An important reason for this is that the mechanisms that cause the diseases at the levels of cells and molecules are unknown. Even though the patients affected by these different diseases clearly do not have identical symptoms, scientists now know that there are important similarities in the changes that occur in the nerve cells as they gradually change their functions and eventually die.

As a new approach for synergy creation and integration of different high-level Nordic laboratories, our NCoE is running a strong scientific training program that brings together students, post-docs and supervisors from the Nordic countries. It includes specialized technical workshops where research methods and reagents are shared between the groups as well as other workshops devoted to specific general skills needed as a scientist. Technical platforms within the NCoE are freely available to all partners.

In summary, the primary missions of the NCoE is:

  • unravel the sequences of events that lead to slow neurodegeneration.
  • identify new therapeutic targets.
  • create a basis for development of new pharmacological therapies.
  • train young scientists and mold them into a future generation of excellent Nordic research leaders in the area of molecular mechanisms of neurodegeneration.